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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients

Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients


Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients


Ebook Free Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients

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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients

Review

“Slightly technical, eminently readable, consistently shocking, occasionally hectoring and unapologetically polemical . . . This is a book that deserves to be widely read, because anyone who does read it cannot help feeling both uncomfortable and angry.” ―The Economist“Ben Goldacre has done it again . . . This is a morbidly fascinating and dispiriting account, yet one which deserves (and needs) to be read and acted upon without delay.” ―Dennis Rosen, Dennis Rosen, The Boston Globe“Read this book. It will make you mad, it will make you scared. And, hopefully, it will bring about some change. ” ―Chris Lee, Ars Technica“A thorough piece of investigative medical journalism. What keeps you turning its pages is the accessibility of Goldacre's writing, . . . his genuine, indignant passion, his careful gathering of evidence and his use of stories, some of them personal, which bring the book to life.” ―Luisa Dillner, The Guardian“Goldacre's research is scrupulous, and lay readers may find themselves converted by his geeky ardor. ” ―The New Yorker“[A]n eye-opening glance into a world of experts who have failed us.” ―The New York Times Book Review“In this searing exposé of the pharmaceutical industry, physician and journalist Goldacre uncovers a cesspool of corrupt practices designed to sell useless or dangerous drugs to an unsuspecting public . . . Goldacre conveys complicated scientific, medical, and ethical issues in simple, clear, plainspoken language that pulls no punches. The result is a smart, infuriating diagnosis of the rotten heart of the medical-industrial complex.” ―Publishers Weekly“A useful guide for policymakers, doctors and the patients who need protection against deliberate disinformation.” ―Kirkus Reviews“Goldacre's essential exposé will prompt readers to ask more questions before automatically popping a doctor-prescribed pill.” ―Karen Springen, Booklist“Smart, funny, clear, unflinching: Ben Goldacre is my hero.” ―Mary Roach, author of Stiff, Spook, and Bonk, on Bad Science“Ben Goldacre is exasperated . . . He is irked, vexed, bugged, ticked off at sometimes inadvertent (because of stupidity) but more often deliberate deceptions perpetrated in the name of science . . . You'll get a good grounding in the importance of evidence-based medicine . . . ‘Studies show' is not good enough, he writes: ‘The plural of "anecdote" is not data.'” ―Katherine Bouton, The New York Times, on Bad Science“One of the best books I've ever read. It completely changed the way I saw the world. And I actually mean it. ” ―Tim Harford, author of The Undercover Economist, on Bad Science“Ben Goldacre lucidly, and irreverently, debunks a frightening amount of pseudoscience, from cosmetics to dietary supplements to alternative medicine. If you want to read one book to become a better-informed consumer and citizen, read Bad Science.” ―Sandeep Jauhar, author of Intern, on Bad Science“This is a much-needed book. Ben Goldacre shows us--with hysterical wit--how to separate the scam artists from real science. In a world of misinformation, this is a rare gem.” ―Timothy Ferriss, author of The 4-Hour Workweek, on Bad Science“Ben Goldacre uses a brilliant mix of science and wit to challenge and investigate alternative therapists and the big pharmaceutical corporations. Bad Science is an invaluable tool for anybody who wants to protect themselves from the snake-oil salesmen of the twenty-first century.” ―Simon Singh, author of Big Bang and Fermat's Last Theorem, on Bad Science“British physician and journalist Ben Goldacre takes aim at quack doctors, pharmaceutical companies and poorly designed studies in extraordinary fashion in Bad Science . . . Goldacre shines in a chapter about bad scientific studies by writing it from the perspective of a make-believe big pharma researcher who needs to bring a mediocre new drug to market. He explains exactly how to skew the data to show a positive result. 'I'm so good at this I scare myself,' he writes. 'Comes from reading too many rubbish trials.'” ―Rachel Saslow, The Washington Post, on Bad Science“Funny and biting . . . While it is a very entertaining book, it also provides important insight into the horrifying outcomes that can result when willful anti-intellectualism is allowed equal footing with scientific methodology.” ―Dennis Rosen, The Boston Globe, on Bad Science“I hereby make the heretical argument that it is time to stop cramming kids' heads with the Krebs cycle, Ohm's law, and the myriad other facts that constitute today's science curricula. Instead, what we need to teach is the ability to detect Bad Science--BS, if you will. The reason we do science in the first place is so that 'our own atomized experiences and prejudices' don't mislead us, as Ben Goldacre of the London School of Hygiene and Tropical Medicine puts it in his new book, Bad Science: Quacks, Hacks, and Big Pharma Flacks. Understanding what counts as evidence should therefore trump memorizing the structural formulas for alkanes.” ―Sharon Begley, Newsweek.com, on Bad Science“Dr. Ben Goldacre's UK bestseller Bad Science: Quacks, Hacks, and Big Pharma Flacks is finally in print in the USA, and Americans are lucky to have it. Goldacre writes a terrific Guardian column analyzing (and debunking) popular science reporting, and has been a star in the effort to set the record straight on woowoo 'nutritionists,' doctors who claim that AIDS can be cured with vitamns, and vaccination/autism scares. Bad Science is more than just a debunking expose (though it's that): it's a toolkit for critical thinking, a primer on statistics and valid study design, a guide to meta-analysis and other tools for uncovering and understanding truth . . . The book should be required reading for everyone who cares about health, science, and public policy.” ―BoingBoing.net on Bad Science

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About the Author

Ben Goldacre is a doctor and a writer. His first book, Bad Science, was an international bestseller and has been translated into twenty-five languages. He lives in London.

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Product details

Paperback: 480 pages

Publisher: Farrar, Straus and Giroux; Reprint edition (April 1, 2014)

Language: English

ISBN-10: 0865478066

ISBN-13: 978-0865478060

Product Dimensions:

5.5 x 1.3 x 8.2 inches

Shipping Weight: 12.8 ounces (View shipping rates and policies)

Average Customer Review:

4.5 out of 5 stars

188 customer reviews

Amazon Best Sellers Rank:

#185,453 in Books (See Top 100 in Books)

Bad Pharma highlights serious issues with the way the pharmaceutical industry works today. In the book Ben highlights the problems with the industry from several angles, how the tests can be tweaked, how negative tests are not published, how you can make a neutral test appear positive by sub-dividing the goals and then emphasize the fluke positive one. He also shows how the medical journals are part of the problem and the issue with ghost written articles. He shows the problems with the regulatory side as well, for example the European Medicines Agency, their lack of transparency, and how they have effectively blocked access to critical data for researchers. All through the book Ben makes use of well documented examples, and all the issues highlighted are well documented and exemplified.The book is written in an easy to access language, and so it reads well. He does repeat himself a bit, so one more round of editing and cleanup before release would probably have been a good idea. Some readers on amazon.co.uk have criticised this, but I don't see it as an issue.You don't need to have a degree in medicine or a higher degree in general to understand the issues Ben highlights.Ben Goldacre runs the Bad Science website (badscience dot net) and has previously written the book Bad Science. Where Bad Science was an attack on quackery and pseudo science, and his website to a large degree has dealt with the same topics, this book is a critical look at the pharmaceutical industry. As such it ought to silence those that have attacked Ben Goldacre for being in the pockets of the Pharmaceutical industry over time.Ben Goldacre has done society a big favour by writing this book. I definitely recommend reading it if you want to understand more about how US and European health care works and what can be done to improve it in the future.

Explaining Big Pharm Problems Using Pop Stars“…the bar is very low: that drugs must only prove that they are better than nothing, even when there are highly effective treatments on the market already.“ — Goldacre, Ben "Bad Pharma: …”Let me explain the above:Say there’s a drug for ‘XYZ Disease’ on the market named “ ‘Yonce ” that is 80 - 85% effective in stopping growth right in its tracks. Most people use ‘Yonce, and are fairly happy with it, but nobody would mind if someone made it 100% effective.Along comes a research company named SwiftMoney and dumps millions into research and development in hopes of marketing a competing drug to “‘Yonce” because wow ‘Yonce is a hit and SwiftMoney wants a piece of the pie.So SwiftMoney churns out a drug named, ‘TaylorSwift,’ however, it turns out all their millions are for naught. The drug they’ve developed is only minimally effective — about 20 - 30% effective in stopping ‘XYZ Disease,’ even worse, in 10% of the subjects tested the drug actually proved harmful.Luckily SwitftMoney is not legally required by the FDA to report, nor publish, negative results of drug trials if they don’t wish to. In that very manner SwiftMoney can carry out 10 clinical trials and publish the results from the 2 trials that had positive outcomes, and bury the 8 trials that showed no favorable outcome, or even worse showed negative outcomes. As long as SwiftMoney can prove that their drug is better than a placebo — a dummy pill — like the drug ‘Friday’ by pharmaceutical company ‘RebeccaBlack’ then the FDA will allow the marketing of ‘Taylor.’So SwiftMoney floods the market with their subpar drug named ‘TaylorSwift’(1) and spends millions and millions in marketing to convince people that they should buy Taylor instead of ‘Yonce(2).Trial data that shows unflattering evidence is simply withheld from doctors and patients, and this practice is commonplace. What we all really need is a nonprofit organization called KANYE to stand up and say: “Look, TaylorSwift, Imma let you market your drug, ‘cause this is a free market economy, but everybody deserves to know that ‘Yonce has the best ‘xyz drug’ of all time, up until this time.” In that way doctors and patients are making actual informed decisions.What I’ve written about is only a small part of how nasty the whole problem truly is, I suggest picking up a copy of “Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients” by Ben Goldacre for yourselves.Thank you for your time.We all need Yeezus!—ewitty(1.) [“This means that real patients are given dummy placebo pills for no good reason, but also that drugs appear on the market which are worse than the treatments we already have.” — Bad Pharma: …”](2.) ["pharmaceutical companies spend tens of billions of pounds every year trying to change the treatment decisions of doctors: in fact, they spend twice as much on marketing and advertising as they do on the research and development of new drugs. — Bad Pharma: …”]

I've always enjoyed when Penn &Teller do a truck and fool me,explain HOW they fooled me ,and then ,having just explained how they do it,fool me once again as they repeat their trick! I find it less enjoyable wen pharmaceutical companies repeatedly pull the wool over my eyes,but I REALLY appreciate Dr. Goldacre showing me so many ways that Pharma uses to trick me . Again and again. What I don't fully understand,as a long-practicing physician in the twilight of my career,is how Pharma can repeatedly change primary outcomes for trials ,rewrite a protocol and pass off negative results as positive results. Well,I didn't understand this before,nor did I understand the prevalence of that cute maneuver, but at least now I understand how commonplace it is and how complicit or willfully stupid the journal editors are who let this go on. Ionnidis' famous article on how what u read in journals is likely NOT true was amazing. This book is just astounding in explaining the old Mark Twain quote "It ain't what u don't know that gits u (or is it your patient?)in trouble, it's what u know for sure that just ain't so." This enjoyable vade mecum explains almost exactly how we get to know so much for sure that" just ain't so." Thanx Dr Goldacre.

Probably the most important book I've read this year. While I've been sceptical of Big Pharma for a long time, I was shocked and horrified to know just how bad things are. There are massive issues around funding, loopholes for approvals, and not publishing unfavourable results skewing the safety and efficiency perceptions of drugs. Bad Pharma isn't anti science - rather the opposite - Ben Goldacre is a doctor and science journalist, and advocates for sticking to the scientific method, full disclosure and advocating for the interest of the patients - not the drug companies. I can't recommend this enough.

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